In a match where the lead changed hands four times, a 19-point haul from centre Matthew Bray, and tries from James Andrew, John Stanfield and Sam Laird, secured Boston’s second win of the season.
The result sees the Blue and Whites move up to sixth in the Midlands 3 East (North).
In a hard-fought encounter, the visitors attacked from the kick off and - for the first quarter - Boston remained firmly on the back foot.
Loughborough’s forwards and backs started impressively and only good defensive tackling prevented try scoring opportunities.
Loughborough missed an early penalty to take the lead after eight minutes.
However, two minutes later they scored the first try to go 0-5 ahead.
In a rare foray, centre James Andrews broke a number of tackles to level the scores, Bray’s conversion moving Boston 7-5 ahead.
Loughborough replied straight a way with a well-executed catch and drive to regain the lead.
In the next four minutes a third try from Loughborough’s winger and a penalty from the 10 metre line by Bray saw the scoreboard stand at 10-15 in favour of the visitors.
At this stage a yellow card to the Loughborough prop disrupted their play and Boston took advantage, recording a penalty via Bray and a try by replacement Stanfield to move Boston 18-15 ahead at half time.
The second half saw the home side start to struggle as injuries forced a reshuffle.
On 51 minutes Bray’s penalty extended the lead to 21-15.
Minutes later an excellent flowing move, which started deep in Boston’s half, involving both forwards and backs, ended with number eight Laird scoring in the corner.
Bray’s conversion moved Boston 28-15 in front.
This seemed to galvanise the visitors, who quickly replied and scored two quick tries within four minutes to reduce the arrears to 28-27.
A tense final five minutes saw Boston hang on before Bray’s drop goal settled the scores.
BOSTON: Scupham, Dowse, Rodgers, Eldin, Dean, Cotton-Betteridge, Laird, Miles, Laidlaw, Baldwin, Halliday, Andrews, Bray, Balsom, Woolston; Replacements: Worboys, Neal, Stanfield.
On Saturday Boston travel to play Nottingham Moderns (KO 3pm).