Tonight will see the first of two temporary right turn bans in place for traffic travelling on John Adams Way from Haven Bridge into South End towards Skirbeck.
The temporary ban lasts from 7pm tonight until 6am tomorrow and will be followed up by the same arrangement next Thursday, October 23.
There will also be a left-only restriction for traffic on South Square joining John Adams Way.
A spokesman said this is for safety reasons while work is done to traffic lights.
The move is part of the drive to finish the roadworks overnight to cut disruption.