Wyberton striker Curtis Yeatman scored all his side’s goals as they dumped Fosdyke out of the Barclays Brokers Willoughby Cup with a 4-1 victory.
The speedy forward opened his account within the first minute to help the Premier side book their place in the semi-finals.
Jimmy Hawkes scored for Fosdyke.
Ali Smith’s penalty was not enough for Coningsby, who went down 2-1 in their derby with Woodhall Spa United.
Dec Wilson and Simon Hyland scored for Fishtoft, who went down 5-2 to Billinghay Athletic.
In their first-round contest, which had previously been postponed, Skegness Town Reserves beat Park United 4-1.
In the Taylors Garages Premier Division, Benington were punished for not taking their chances as they were edged out 2-1 in their derby duel at Old Leake.
Adam Lester and Bert Snaith were the matchwinners, with Tim Bell netting for Benington.
Spilsby Town and Kirton Town were involved in a high-scoring encounter at Ancaster Avenue, with the hosts winning 5-2.
Taylors Peugeot Division One leaders Freiston Reserves suffered a surprise 2-1 home defeat to Skegness United Reserves, Freiston’s finish being an own goal.
Wyberton Reserves and Spalding Town, who had two men sent off, drew 2-2, Nicky Syndercombe and Steve Favell scoring for the hosts.
Scott Mackay hit two penalties as Wrangle United beat Wainfleet United 6-2, Tom Hill, Owen Morgan, Bobby Smith and Joe Pitcher were also on target.
Richard Barker scored twice for Sutterton in their 4-1 home win against Leverton to keep their Taylors Ford Division Two promotion hopes alive. Adam Abell and Danny Clayton were also on target for the home side.
Fishtoft Reserves slumped to another heavy defeat when they entertained Coningsby Reserves.
Danny Cottingham hit four of his side’s goals in a 5-0 away win, with Steven Hunter also getting on the scoresheet.
Taylors Vauxhall Division Three action saw FC Hammers beat Tulip thanks to a solitary Jack Tate goal.
Any teams wishing to enter The Boston Saturday Football League are asked to ensure that they have their fully completed application forms submitted to secretary Elaine Wilson, by May 1.
Forms can be obtained by calling 01205 354190.
Four matches fell foul of waterlogged pitches this week.
Pointon v Old Doningtonians, Pointon Reserves v Park United, Old Dons reserves v Nelson and Holbeach Bank Reserves v Sutterton Reserves were postponed.