Boston Town were beaten 3-0 at Northampton Sileby Rangers on Saturday.
The Poachers have now gone eight matches without victory and sit second bottom of the United Counties League’s Premier Division.
Michael Byrne, Andrew Hall and Stuart MacMichael netted the winning goals.
The Poachers handed a debut to Conor Minor, who has been playing for Skegness United in the East Lincolnshire Combinations League.
Meanwhile, Jordan Nuttell made an appearance from the bench, only his fourth run out of the campaign due to injury.